Original

Disseminated acute encephalomyelitis in children

J.A. Peña, C. Montiel-Nava, F. Hernández, E. Medrano, O. Valbuena, J.J. Cardozo [REV NEUROL 2002;34:163-168] PMID: 11988912 DOI: https://doi.org/10.33588/rn.3402.2001271

OPEN ACCESS

Volumen 34 | Number 02 | Nº of views of the article 17.439 | Nº of PDF downloads 2.054 | Article publication date 16/01/2002

Download PDF Castellano Citation Search in PubMed

Share in:

Go to another issue

ABSTRACT

INTRODUCTION Disseminated acute encephalomyelitis (DAE) is an autoimmune inflammatory condition, usually monophasic with gradual resolution, polysymptomatic, usually in relation to a virus, bacteria or immunizations but may also occur in the absence of any obvious infection. OBJECTIVE. To describe DAE, its aetiology, clinical features, diagnosis and treatment. Also to analyze these aspects with regard to a series of 13 children with DAE.

RESULTS The clinical condition started with fever in 61% of the patients. The commonest neurological findings were sensory deterioration, convulsions and motor disorders (paresias). The cerebrospinal fluid was abnormal in four patients. MR showed hyperintense lesions of multifocal distribution, predominantly in the subcortical white matter. All patients were treated with intravenous methylprednisolone at a dose of 20-30 mg/kg. Clinical follow up showed complete recovery in 11/13 patients and mild sequelae in two cases.

CONCLUSIONS Diagnosis of DAE is based on suggestive clinical data and MR findings. MR is very sensitive in detecting demyelinating lesions and is the method of choice for confirmation of the diagnosis. DAE is characterized by a satisfactory clinical course with simultaneous resolution of the demyelinating lesions. KeywordsDemyelinating disorders Disseminated acute encephalomyelitis Magnetic resonance CategoriesNeuropediatría

FULL TEXT (solo disponible en lengua castellana / Only available in Spanish)

Acceso directo al último número

Último Podcast

Original

Disseminated acute encephalomyelitis in children