Revisión

Síndrome de Guillain-Barré

A. Tellería-Díaz, D.J. Calzada-Sierra [REV NEUROL 2002;34:966-976] PMID: 12134330 DOI: https://doi.org/10.33588/rn.3410.2001280

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Volumen 34 | Number 10 | Nº of views of the article 16.897 | Nº of PDF downloads 8.892 | Article publication date 16/05/2002

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ABSTRACT

OBJECTIVE. To review about this disorder, with emphasis on the intensive care of severe Guillain-Barré syndrome (GBS). DEVELOPMENT. GBS is an acute immunemediated inflammatory polyneuropathy that may lead to quadriparesis, ventilatory failure, and autonomic dysfunction but also to many general medical problems that have great bearing on outcome. Therefore severe GBS patients require admission into an intensive care unit (ICU), where in addition to the disorders mentioned before, other complications can arise. The neurologist who plans to deal comprehensively with these patients must be familiar with therapy for infections, nutrition, fluid management, and selected aspects of pulmonary medicine as well as the indications for and complications of plasma exchange and gammaglobulin infusion.

CONCLUSIONS With modern intensive care support, the outcome is excellent (>80% recovery), although in many cases a persistent residual paresis occurs. Because GBS is largely selflimited, the skill daily cares of these patients in an ICU contributes as much, or more, to the overall outcome of an individual patient as do specific immune therapies. KeywordsCritical illness Dysautonomia Gammaglobulin infusion GuillainBarré syndrome Intensive care Neurologic emergencies Plasmapheresis Polyneuropathy Respiratory failure CategoriesNervios periféricos, unión neuromuscular y músculo

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Revisión

Síndrome de Guillain-Barré