Nota Clínica

Cerebral venous thrombosis as the presenting symptom of systemic lupus erythematosus

P. Cardona-Portela, C. Casasnovas-Pons, M. Moral-Torres, F. Rubio-Borrego [REV NEUROL 2004;39:30-34] PMID: 15257524 DOI: https://doi.org/10.33588/rn.3901.2002544

OPEN ACCESS

Volumen 39 | Number 01 | Nº of views of the article 8.935 | Nº of PDF downloads 842 | Article publication date 01/07/2004

Download PDF Castellano Citation Search in PubMed

Share in:

Go to another issue

ABSTRACT

INTRODUCTION Cerebral venous thrombosis (CVT) is an infrequent process in systemic lupus erythematosus. We report the case of a female patient whose initial manifestation of lupus was a CVT. CASE RESPORT. A 30-year-old female who presented headaches and diminished visual acuity; on exploring the patient bilateral papilloedema was found. Magnetic resonance imaging revealed the presence of a venous thrombosis in the superior and transversal longitudinal sinus. Complementary explorations showed high levels of antinuclear antibodies with leukopenia and proteinuria. Antiphospholipid antibodies were negative. Following treatment with anticoagulants, the patient’s condition improved both clinically and radiologically. Months later a biopsy was performed and revealed a grade IV diffuse glomerulonephritis.CONCLUSION. In systemic lupus erythematosus, phenomena such as CVT can be the initial form of presentation of the disease. The presence of antiphospholipid antibodies plays a partial role in CVT; other phenomena, such as inflammatory processes, should also be taken into account. KeywordsAntiphospholipid Lupus anticoagulant Systemic lupus erythematosus Venous thrombosis

FULL TEXT (solo disponible en lengua castellana / Only available in Spanish)

Acceso directo al último número

Último Podcast

Nota Clínica

Cerebral venous thrombosis as the presenting symptom of systemic lupus erythematosus