Original

FUNCTIONAL MAGNETIC RESONANCE IMAGING OF THE VISUAL CORTEX: RELATION BETWEEN STIMULUS INTENSITY AND BOLD RESPONSE

J. Álvarez-Linera Prado, M. Ríos-Lago, H. Martín-Álvarez, J.A. Hernández-Tamames, J. Escribano-Vera, M. Sánchez del Río [REV NEUROL 2007;45:147-151] PMID: 17661273 DOI: https://doi.org/10.33588/rn.4503.2006611

OPEN ACCESS

Volumen 45 | Number 03 | Nº of views of the article 8.363 | Nº of PDF downloads 596 | Article publication date 01/08/2007

Download PDF Castellano Citation Search in PubMed

Share in:

Go to another issue

ABSTRACT

INTRODUCTION Visual system is a high interest topic in neuroscience research. The new neuroimaging techniques, such as functional magnetic resonance imaging (fMRI), allow us to quickly improve our knowledge on the visual system using non-invasive methods. This work examines the effect of small changes in the intensity of a visual stimulus over the BOLD response in the visual cortex. AIMS. To perform a detailed analysis of the visual cortex reaction to different intensities of a light source and to verify the ties between the intensity of the visual stimulus and the cortical response.

SUBJECTS AND METHODS Using fMRI (3 T), we registered BOLD response (area and intensity of the signal change) in 20 photophobic patients and 20 controls while viewing different stimulus intensities from a light source.

RESULTS We found a direct relation between stimulus intensity and occipital response. We show that cortical reactivity is higher in patients with photophobia than normal controls, specially for the lower and medium intensities.

CONCLUSIONS fMRI is a valid and robust technique to register consistent and reproducible responses in different groups of subjects. It is useful for the study of normal cortex functioning as well as for clinical use. KeywordsBOLD response Functional neuroimaging Magnetic resonance imaging Occipital cortex Photophobia Vision CategoriesInfecciones Neuroimagen Neuropsiquiatría

FULL TEXT (solo disponible en lengua castellana / Only available in Spanish)

Acceso directo al último número

Último Podcast

Original

FUNCTIONAL MAGNETIC RESONANCE IMAGING OF THE VISUAL CORTEX: RELATION BETWEEN STIMULUS INTENSITY AND BOLD RESPONSE

¡CONVIÉRTASE EN USUARIO PREMIUM DE NEUROLOGIA.COM!

Al hacerse premium, está apoyándonos para que Revista de Neurología siga siendo uno de los referentes de habla hispana en la difusión del conocimiento en neurociencias. ¡Gratuita tanto para autores como para todos los usuarios de la web!