Citicoline: pharmacological and clinical review, 2010 update

J.J. Secades [REV NEUROL 2011;52 (Supl. 2):S1-S62] PMID: 21432836 DOI: OPEN ACCESS
Volumen 52 | Number S02 | Nº of views of the article 8.780 | Nº of PDF downloads 7.257 | Article publication date 14/03/2011
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ABSTRACT Artículo en español English version
This review is based on the previous one published in 2006 –Secades JJ, Lorenzo JL. Citicoline: pharmacological and clinical review, 2006 update. Methods Find Exp Clin Pharmacol 2006; 28 (Suppl B): S1-56–, incorporating the new references until now, having all the information available to facilitate the access to the información in one document. This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved the most important experimental and clinical data in both indications. KeywordsAlcoholismAlzheimer diseaseAmblyopiaApoptosisCDP-cholineCerebral edemaCerebral ischemiaCiticolineCognitive disorderDrug addictionGlaucomaHead injuryMemoryNeuronal membraneNeuroplasticityNeuroprotectionNeurorepairNeurotransmissionParkinson diseasePhosphatidylcholinePhospholipaseSenile dementiaStrokeStructural phospholipidsTraumatic brain injury CategoriesDemenciaDependenciasNeurodegeneraciónNeuropsicologíaNeuropsiquiatríaPatología vascularTrastornos del movimientoTraumatismos
FULL TEXT Artículo en español English version