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Citicoline: pharmacological and clinical review, 2016 update

J.J. Secades [REV NEUROL 2016;63 (Supl. 3):S1-S73] PMID: 28417449 DOI: https://doi.org/10.33588/rn.63S03.2016508 OPEN ACCESS
Volumen 63 | Number S03 | Nº of views of the article 10.252 | Nº of PDF downloads 606 | Article publication date 23/12/2016
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ABSTRACT Artículo en español English version
This review is based on the previous one published in 2010 –Secades JJ. Citicoline: pharmacological and clinical review, 2010 update. Rev Neurol 2011; 52 (Suppl 2): S1-62–, incorporating 183 new references, having all the information available to facilitate the access to the information in one document. This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved the most important experimental and clinical data in both indications. KeywordsAlcoholismAlzheimer diseaseAmblyopiaApoptosisCDP-cholineCerebral edemaCerebral ischemiaCiticolineCognitive disorderDrug addictionGlaucomaHead injuryMemoryMild cognitive impairmentNeuronal membraneNeuroplasticityNeuroprotectionNeurorepairNeurotransmissionParkinson diseasePhosphatidylcholinePhospholipaseRemyelinationSenile dementiaStrokeStructural phospholipidsTraumatic brain injury CategoriesDemenciaNeurodegeneraciónNeuropsicologíaPatología vascularTrastornos del movimiento
FULL TEXT Artículo en español English version