Tabla I. Características sociodemográficas y antecedentes personales y familiares. |
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n |
% |
||
Sexo |
Femenino |
37 |
58,7 |
Masculino |
26 |
41,3 |
|
Edad al inicio del protocolo (años) a |
29 (24-36) |
||
Edad al inicio de la enfermedad (años) a |
4 (1,5-14) |
||
Tiempo de evolución de la epilepsia (años) a |
22 (15-28) |
||
Crisis por mes a |
8 (3-16) |
||
Fármacos antiepilépticos históricos a |
5 (4-6) |
||
Fármacos antiepilépticos actuales a |
3 (2-3) |
||
Escolaridad |
Ninguna |
4 |
6,4 |
Educación especial |
2 |
3,2 |
|
Primaria incompleta |
8 |
12,7 |
|
Primaria completa |
7 |
11,1 |
|
Bachiller incompleto |
5 |
7,9 |
|
Bachiller completo |
21 |
33,3 |
|
Técnica |
5 |
7,9 |
|
Universitaria |
11 |
17,5 |
|
Antecedentes personales |
Ninguno |
27 |
42,9 |
Retraso del neurodesarrollo |
9 |
14,3 |
|
Infección del sistema nervioso central |
8 |
12,7 |
|
Prematuro |
4 |
6,4 |
|
Crisis febril |
4 |
6,4 |
|
Embarazo gemelar |
4 |
6,4 |
|
Síndrome alcohólico fetal |
3 |
4,8 |
|
Neurocisticercosis |
2 |
3,2 |
|
Hipoxia |
2 |
3,2 |
|
Embarazo controlado |
1 |
1,6 |
|
Esclerosis tuberosa |
1 |
1,6 |
|
Antecedentes patológicos |
Migraña |
3 |
4,8 |
Hipertensión arterial |
1 |
1,6 |
|
Asma |
1 |
1,6 |
|
Quirúrgicos |
2 |
3,2 |
|
Antecedentes familiares de epilepsia |
Abuelos |
1 |
1,6 |
Hermanos |
4 |
6,4 |
|
Tío/a |
8 |
12,7 |
|
Primo/a |
9 |
14,3 |
|
Diagnóstico neurológico |
Normal |
43 |
68,3 |
Retraso mental leve |
10 |
15,9 |
|
Retraso mental moderado |
7 |
11,1 |
|
Retraso mental grave |
3 |
4,8 |
|
a Mediana (rango intercuartílico). |
Tabla II. Análisis de fiabilidad por coeficiente α de Cronbach total y si se elimina el elemento (ítem) de la escala QOLIE-10. |
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α de Cronbach |
α de Cronbach basada en los |
n de elementos (10) |
|||
Ítem |
Media de la |
Varianza de la |
Correlación |
Correlación |
α de Cronbach |
Q1 |
28,1231 |
52,516 |
0,921 |
0,925 |
0,977 |
Q2 |
28,2308 |
54,555 |
0,905 |
0,920 |
0,979 |
Q3 |
28,2923 |
50,960 |
0,932 |
0,914 |
0,977 |
Q4 |
28,4154 |
50,028 |
0,910 |
0,914 |
0,978 |
Q5 |
28,0923 |
51,460 |
0,921 |
0,945 |
0,977 |
Q6 |
28,2154 |
49,390 |
0,944 |
0,961 |
0,977 |
Q7 |
28,0308 |
51,843 |
0,962 |
0,973 |
0,976 |
Q8 |
28,3692 |
54,674 |
0,842 |
0,794 |
0,980 |
Q9 |
28,7077 |
51,929 |
0,896 |
0,842 |
0,978 |
Q10 |
28,4000 |
54,213 |
0,859 |
0,795 |
0,979 |
Tabla III. Matriz de correlaciones interelemento (ítem) y necesidad de realización de análisis factorial. |
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Ítem |
Q1 |
Q2 |
Q3 |
Q4 |
Q5 |
Q6 |
Q7 |
Q8 |
Q9 |
Q10 |
Q1 |
1,000 |
0,876 |
0,874 |
0,806 |
0,901 |
0,904 |
0,939 |
0,800 |
0,794 |
0,791 |
Q2 |
0,876 |
1,000 |
0,879 |
0,860 |
0,841 |
0,812 |
0,881 |
0,724 |
0,828 |
0,865 |
Q3 |
0,874 |
0,879 |
1,000 |
0,865 |
0,830 |
0,920 |
0,881 |
0,817 |
0,853 |
0,843 |
Q4 |
0,806 |
0,860 |
0,865 |
1,000 |
0,871 |
0,894 |
0,879 |
0,735 |
0,860 |
0,815 |
Q5 |
0,901 |
0,841 |
0,830 |
0,871 |
1,000 |
0,885 |
0,964 |
0,775 |
0,832 |
0,767 |
Q6 |
0,904 |
0,812 |
0,920 |
0,894 |
0,885 |
1,000 |
0,934 |
0,853 |
0,841 |
0,795 |
Q7 |
0,939 |
0,881 |
0,881 |
0,879 |
0,964 |
0,934 |
1,000 |
0,826 |
0,854 |
0,820 |
Q8 |
0,800 |
0,724 |
0,817 |
0,735 |
0,775 |
0,853 |
0,826 |
1,000 |
0,822 |
0,714 |
Q9 |
0,794 |
0,828 |
0,853 |
0,860 |
0,832 |
0,841 |
0,854 |
0,822 |
1,000 |
0,807 |
Q10 |
0,791 |
0,865 |
0,843 |
0,815 |
0,767 |
0,795 |
0,820 |
0,714 |
0,807 |
1,000 |
Se observa el resultado en las pruebas de adecuación de la muestra de Kayser-Meyer-Olkin (0,891) y de esfericidad de Bartlett (χ2 = 1.080,211; gl. = 45; sig. = 0). Ambos análisis resultaron significativos y señalan que la base de datos cumple los requisitos para llevar a cabo el análisis factorial. |
Tabla IV. Variabilidad de cada ítem expresada como comunalidad, realizada por el método de extracción de análisis de componentes principales. |
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Ítem |
Inicial |
Extracción |
Q1 |
10,000 |
0,880 |
Q2 |
10,000 |
0,855 |
Q3 |
10,000 |
0,894 |
Q4 |
10,000 |
0,859 |
Q5 |
10,000 |
0,876 |
Q6 |
10,000 |
0,911 |
Q7 |
10,000 |
0,940 |
Q8 |
10,000 |
0,755 |
Q9 |
10,000 |
0,838 |
Q10 |
10,000 |
0,784 |
Tabla V. Matriz de varianza total explicada por componentes, realizada por el método de extracción de análisis de componentes principales. |
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Autovalores iniciales |
|||
Total |
% de la varianza |
% acumulado |
|
Componente 1 |
8,593 |
85,934 |
85,934 |
Componente 2 |
0,369 |
3,687 |
89,620 |
Componente 3 |
0,303 |
3,029 |
92,650 |
Componente 4 |
0,227 |
2,273 |
94,923 |
Componente 5 |
0,171 |
1,711 |
96,634 |
Componente 6 |
0,134 |
1,336 |
97,970 |
Componente 7 |
0,094 |
0,935 |
98,905 |
Componente 8 |
0,061 |
0,611 |
99,516 |
Componente 9 |
0,033 |
0,332 |
99,847 |
Componente 10 |
0,015 |
0,153 |
100 |
Tabla VI. Matriz de componentes finales. |
|
Componente 1 |
|
Vitalidad |
0,938 |
Estado de ánimo |
0,925 |
Conducción |
0,946 |
Memoria |
0,927 |
Trabajo |
0,936 |
Vida social |
0,954 |
Efectos físicos de los fármacos antiepilépticos |
0,970 |
Efectos mentales de los fármacos antiepilépticos |
0,869 |
Preocupación por las crisis |
0,916 |
Calidad de vida global |
0,886 |
Validity and reliability of the QOLIE-10 instrument for assessing health related quality of life in epilepsy of refractory epilepsy adult patients at a Colombian neurological center Aim. To determine feasibility, reliability and validity of the shortened version of the Quality of Life in Epilepsy Inventory-10 (QOLIE-10) in a population of refractory epilepsy adult patients in the Colombian Caribbean. Patients and methods. Data were collected from 63 adult refractory epilepsy patients. The ten items of QOLIE-10 were derived from the Spanish version of QOLIE-89. We assess feasibility, validity, factorial analysis with communalities, reliability through internal consistency and sensitivity to change. Results. Clinical and demographic features were determined; quality of life was established through frequencies. Construct validity: through factor analysis communalities there were no items considered irrelevant and were grouped into one single dimension. Kaiser-Meyer-Olkin: 0.891. Bartlett’s test of sphericity: p < 0.001. Average intraclass correlation coefficient 0.843. The internal consistency reliability coefficient (Cronbach’s α) was 0.98. The QOLIE-10 questionnaire for the assessment of health-related quality of life was validated in Spanish for adult patients with refractory epilepsy with excellent validity, reliability parameters and easy, quick filling. Conclusions. The QOLIE-10 questionnaire is a valid and reliable tool for use in adult patients with refractory epilepsy in Colombia. Health professionals are encouraged to use this questionnaire to routinely examine the influences of the disease process in epilepsy patients. Key words. Epilepsy. QOLIE-10. Quality of life. Refractory epilepsy. Surveys and questionnaires. Validation studies. |