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12th Post-ECTRIMS Meeting: review of the novelties from the 2019 ECTRIMS Congress (I)

O. Fernández, Y. Aladro, R. Arroyo, Ll. Brieva, M.C. Calles-Hernández, P. Carrascal, M. Comabella, L. Costa-Frossard, S. Eichau, J.A. García-Merino, R. Ginestal, I. González, G. Izquierdo, M.L. Martínez-Ginés, J.E. Meca-Lallana, M.M. Mendibe-Bilbao, A. Oterino, J.M. Prieto, J. Río, Ll. Ramió-Torrentà, L. Romero-Pinel, N. Téllez, A. Rodríguez-Antigüedad Journal 70(10) ● Publication date 16/05/2020 ● Revisión ● Views 2296 ● Downloads 182 Castellano English

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Fernandez O Aladro Y Arroyo R Brieva Ll Calles-Hernandez MC Carrascal P Comabella M Costa-Frossard L Eichau S Garcia-Merino JA Ginestal R Gonzalez I Izquierdo G Martinez-Gines ML Meca-Lallana JE Mendibe-Bilbao MM Oterino A Prieto JM Rio J Ramio-Torrenta Ll Romero-Pinel L Tellez N Rodriguez-Antiguedad A

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Biomarkers Cognition ECTRIMS Multiple sclerosis Pathophysiology Post-ECTRIMS Remyelination

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[REV NEUROL 2020;70:379-390] PMID: 32390131 DOI: https://doi.org/10.33588/rn.7010.2020121

INTRODUCTION. Like every year, after the ECTRIMS Congress, renowned Spanish neurologists who are experts in multiple sclerosis presented the main novelties in research in this field at the Post-ECTRIMS Meeting.

AIM. To summarise the content presented at the 12th edition of the Post-ECTRIMS Meeting, which took place in September 2019 in Sevilla and is presented in two parts. DEVELOPMENT. This first part addresses the latest studies on vitamin D deficiency and the discrepancies that currently exist regarding its treatment. The advances made in epigenetics allow us to present this approach as a possible biomarker of multiple sclerosis. An account is provided to explain the growing importance of imaging techniques to detect atrophy and other phenomena that occur during the disease, such as changes in iron concentration or remyelination processes, which allow us to further our understanding of the mechanisms of cortical pathology, and the dimensionality of neurodegeneration during its course. Findings related to immunological mechanisms and advances in potential antigen-specific therapies are discussed. The contribution presents the latest studies on the assessment of cognitive impairment and its rehabilitation, which are becoming increasingly important due to the high prevalence of these disorders and the absence of their systematic assessment in clinical practice. Finally, the unmet social and health needs of multiple sclerosis patients in our country are presented, with emphasis on the current deficits in the system of social protection.

Keywords Biomarkers Cognition ECTRIMS Multiple sclerosis Pathophysiology Post-ECTRIMS Remyelination Classified in Esclerosis múltiple - Neuropsicología

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Biomarkers Cognition ECTRIMS Multiple sclerosis Pathophysiology Post-ECTRIMS Remyelination

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Biomarkers Cognition ECTRIMS Multiple sclerosis Pathophysiology Post-ECTRIMS Remyelination

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12th Post-ECTRIMS Meeting: review of the novelties from the 2019 ECTRIMS Congress (I)

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Máster en Sueño: Fisiología y Medicina

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