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A longitudinal study of patients with Parkinson’s disease (ELEP): aims and methodology

Grupo ELEP, P. Martínez-Martín, G. Linazasoro-Cristóbal, J. Kulisevsky, M. Aguilar-Barberà, J. de Pedro-Cuesta, E. Cubo, M.J. Forjaz, A. Bergareche, J.C. Martínez-Castrillo, M. Blázquez-Estrada, L. Menéndez-Guisasola, C. Salvador-Aguiar, S. González-González, A. Bayés-Rusiñol, L. Vela, J.J. Balseiro-Gómez, A. Ortega-Moreno, S. García-Muñozguren, B. Frades-Payo, S. Arroyo-Velasco, C. Durán-Herrera, J. Duarte, A. Mendoza-Rodríguez, M.F. Rodríguez-Sanz, L.J. López del Val, J.R. Chacón, J.M. Fernández-García, J. Benito-León, V.M. Campos-Arillo, F. Vivancos-Matellano, A. Rojo, M. Álvarez-Saúco, C. Leiva-Santana, P. Mir, M. Carballo-Cordero, A. Palomino-García, J.A. Burguera, M.J. Catalán, M.R. Luquin-Piudo Journal 42(06) ● Publication date 16/03/2006 ● Protocolo ● Views 2276 ● Downloads 1384 Castellano English Português

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Grupo ELEP Martinez-Martin P Linazasoro-Cristobal G Kulisevsky J Aguilar-Barbera M de Pedro-Cuesta J Cubo E Forjaz MJ Bergareche A Martinez-Castrillo JC Blazquez-Estrada M Menendez-Guisasola L Salvador-Aguiar C Gonzalez-Gonzalez S Bayes-Rusinol A Vela L Balseiro-Gomez JJ Ortega-Moreno A Garcia-Munozguren S Frades-Payo B Arroyo-Velasco S Duran-Herrera C Duarte J Mendoza-Rodriguez A Rodriguez-Sanz MF Lopez del Val LJ Chacon JR Fernandez-Garcia JM Benito-Leon J Campos-Arillo VM Vivancos-Matellano F Rojo A Álvarez-Sauco M Leiva-Santana C Mir P Carballo-Cordero M Palomino-Garcia A Burguera JA Catalan MJ Luquin-Piudo MR

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Assessment Long-term follow-up Methods Parkinson’s disease

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[REV NEUROL 2006;42:360-365] PMID: 16575773 DOI: https://doi.org/10.33588/rn.4206.2006041

INTRODUCTION AND DEVELOPMENT. Parkinson’s disease (PD) is a chronic and progressive disorder. It produces a significant burden not only for patients, but also for their family and caregivers, with a major socio-economic impact on society. Current knowledge on PD is characterized by scarce information about the evolutionary course of: 1) the non-motor PD features; 2) impact of non-motor PD features on disability and health related quality of life (HRQL) impairment; 3) factors related to disability and HRQL determinants; 4) factors that speed or slow the progression of PD; 5) differential long-term effect of available PD therapeutic schedules and their relationships with disability, complications, and HRQL; and 6) impact of the disease on patients’ caregivers. In addition, heterogeneity in the metric quality of the applied measures and selection bias are frequently found. CONCLUSION. Due to the aforementioned limitations and from a multidimensional perspective, a new longitudinal study in PD is deemed necessary. The longitudinal study of PD patients (ELEP) includes a long-term follow-up of never before sistematically assessed aspects, will allow to increase the global knowledge about PD.

Keywords Assessment Long-term follow-up Methods Parkinson’s disease Classified in Neurodegeneración - Trastornos del movimiento

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Assessment Long-term follow-up Methods Parkinson’s disease

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A longitudinal study of patients with Parkinson’s disease (ELEP): aims and methodology

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