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Strokes caused by infection in the tropics

F.J. Carod-Artal [REV NEUROL 2007;44:755-763] PMID: 17583870 DOI: https://doi.org/10.33588/rn.4412.2006568

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Volumen 44 | Number 12 | Nº of views of the article 6.129 | Nº of PDF downloads 712 | Article publication date 16/06/2007

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ABSTRACT

INTRODUCTION Almost three out of every four people in the world who suffer a fatal stroke live in developing countries. A number of different tropical diseases may appear in Europe in the coming years as a consequence of the demographic change that is being brought about by migratory flows. We review the main infectious causes of strokes in the tropics. DEVELOPMENT. There are estimated to be 500 million cases of malaria every year. Cerebral malaria can cause cerebral oedema, diffuse or focal compromise of the subcortical white matter and cortical, cerebellar and pontine infarctions. Chagas disease is an independent risk factor for stroke in South America. At least 20 million people have the chronic form of Chagas disease. The main prognostic factors for Chagas-related stroke are the presence of apical aneurysms, arrhythmia and heart failure. Vascular complications of neurocysticercosis include transient ischemic attacks, ischemic strokes due to angiitis and intracranial haemorrhages. The frequency of cerebral infarction associated with neurocysticercosis varies between 2% and 12%. Gnathostomiasis is a cause of subarachnoid haemorrhage in south-east Asia. Other less common causes of stroke are viral haemorrhagic fevers due to arenavirus and flavivirus.

CONCLUSIONS Several diseases that are endemic in the tropics can be responsible for up to 10% of the cases of strokes in adults. KeywordsChagas Cysticercosis Gnathostomiasis Malaria Stroke Tropics CategoriesPatología vascular

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