Original

Primary lymphoma of the central nervous system: 20 years’ experience in a referral hospital

A.L. Calderón-Garcidueñas, J. Pacheco-Calleros, E. Castelán-Maldonado, F.C. Nocedal-Rustrián [REV NEUROL 2008;46:84-88] PMID: 18247279 DOI: https://doi.org/10.33588/rn.4602.2007507

OPEN ACCESS

Volumen 46 | Number 02 | Nº of views of the article 4.668 | Nº of PDF downloads 335 | Article publication date 16/01/2008

Download PDF Castellano Citation Search in PubMed

Share in:

Go to another issue

ABSTRACT

INTRODUCTION Primary central nervous system lymphomas (PCNSL) are rare neoplasms.

AIM To study the clinical aspects and the immuno-phenotype of all cases of PCNSL in a 20 years lapse in a referral hospital in Northeastern Mexico.

PATIENTS AND METHODS From January 1986 to December 2005 all PCNSL histologically confirmed were studied.

RESULTS The primary lymphomas were 1% of malignant central nervous system neoplasms. 21 cases were studied (ages from 9-70 years) with male predominance (2:1). 24% patients had immuno-suppression. The more frequent clinical data were: papilledema (71%), headache (62%), paresis (48%) and seizures (33%). 33% of patients died during the first six months after diagnosis. The T lymphomas were 19% of cases and corresponded to small cell type.

CONCLUSIONS PCNSL are still a diagnostic challenge. Multicenter studies are required in order to determine the best treatment protocol. KeywordsCentral nervous system Immunophenotype Lymphoma

FULL TEXT (solo disponible en lengua castellana / Only available in Spanish)

Acceso directo al último número

Último Podcast

Original

Primary lymphoma of the central nervous system: 20 years’ experience in a referral hospital

¡CONVIÉRTASE EN USUARIO PREMIUM DE NEUROLOGIA.COM!

Al hacerse premium, está apoyándonos para que Revista de Neurología siga siendo uno de los referentes de habla hispana en la difusión del conocimiento en neurociencias. ¡Gratuita tanto para autores como para todos los usuarios de la web!