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Multiple sclerosis epidemiological situation update: pertinence and set-up of a population based registry of new cases in Catalonia

S. Otero-Romero, J. Batlle, I. Bonaventura, L. Brieva, E. Bufill, A. Cano, O. Carmona, A. Escartín, M. Marco, E. Moral, E. Munteis, C. Nos, I. Pericot-Nierga, H. Perkal, Ll. Ramió-Torrentà, C. Ramo-Tello, A. Saiz, J. Sastre-Garriga, M. Tintoré, J. Vaqué, X. Montalbán, en representación del Grupo de Trabajo del Registro de Esclerosis Múltiple de Cataluña [REV NEUROL 2010;50:623-633] PMID: 20473839 DOI: https://doi.org/10.33588/rn.5010.2009623

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Volumen 50 | Number 10 | Nº of views of the article 6.559 | Nº of PDF downloads 1.051 | Article publication date 16/05/2010

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ABSTRACT

INTRODUCTION The first epidemiological studies on multiple sclerosis (MS) around the world pictured a north to south latitudinal gradient that led to the first genetic and environmental pathogenic hypothesis. MS incidence seems to be increasing during the past 20 years based on recent data from prospective studies performed in Europe, America and Asia. This phenomenon could be explained by a better case ascertainment as well as a change in causal factors. The few prospective studies in our area together with the increase in the disease in other regions, justifies an epidemiological MS project in order to describe the incidence and temporal trends of MS. DEVELOPMENT. A prospective multicenter MS registry has been established according to the actual requirements of an epidemiological surveillance system. Case definition is based on the fulfillment of the McDonald diagnostic criteria. The registry setting is the geographical area of Cataluña (northeastern Spain), using a wide network of hospitals specialized in MS management. CONCLUSION. Recent epidemiological studies have described an increase in MS incidence. In order to contrast this finding in our area, we consider appropriate to set up a population based registry. KeywordsEpidemiological surveillance Epidemiology Information systems Multiple sclerosis Registry CategoriesEsclerosis múltiple

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Multiple sclerosis epidemiological situation update: pertinence and set-up of a population based registry of new cases in Catalonia

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