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Long-term development of carotid stenosis treated by endovascular means: a prospective study in a neurovascular unit

A. Lago, F. Aparici, V. Parkhutik, J.I. Tembl, E. Mainar, V. Vázquez-Añón, B. Claramonte [REV NEUROL 2011;53:538-544] PMID: 22012817 DOI: https://doi.org/10.33588/rn.5309.2011369

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Volumen 53 | Number 09 | Nº of views of the article 4.874 | Nº of PDF downloads 408 | Article publication date 01/11/2011

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ABSTRACT

AIMS. Even today, unlike endarterectomy, long-term development in carotid angioplasty has still not been well defined. The aim of this study is to describe both the short- and long-term development and the rate of restenosis in a consecutive series of patients with carotid stenosis who underwent endovascular treatment at the Hospital Universitario La Fe; a distinction is made between patients with and without symptoms.

PATIENTS AND METHODS From 1999 to 2010, 426 patients were submitted to a carotid angioplasty (25.5% were asymptomatic patients). Clinical follow-ups were conducted in the case of 374 patients. They had annual check-ups and every year a neurosonological study was performed. The aim was to determine what complications occurred during the first 30 days, as well as the long-term complications, to establish the rate of restenosis and to evaluate possible differences between patients with and without symptoms.

RESULTS The morbidity and mortality rate in the first month was 4.2% (4.4% in symptomatic patients and 3.8% in asymptomatic patients). The mean follow-up time was 55 months: 8% of patients presented strokes, 11% suffered from myocardial infarct and 24.3% died, with no significant differences between patients with or without symptoms. The rate of restenosis was 17.3% at five years, 7.5% equal to or above 50% and, of those, 1.1% were symptomatic. Five patients with significant restenosis were successfully treated with endovascular techniques.

CONCLUSIONS Carotid angioplasty is an effective, safe technique in the hands of an experienced professional; our findings are good, both in the short and the long term, with a low rate of restenosis. If this latter condition occurs, vascular intervention techniques are safe and efficient. KeywordsCarotid angioplasty Carotid restenosis Carotid stenosis Carotid stent Ischaemic stroke Prognosis of carotid angioplasty CategoriesPatología vascular Técnicas exploratorias

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Original

Long-term development of carotid stenosis treated by endovascular means: a prospective study in a neurovascular unit