Table I. Number of valproate prescriptions in the main and entire pre- and post-implementation periods for both study panels in Spain.
|
|
Overall population
|
Women of childbearing potential
(13-49 years of age)
|
Pre-implementation period
|
Post-implementation period
|
Pre-implementation period
|
Post-implementation period
|
Main: 21 months
(entire: 36 months)
|
Main: 30 months
(entire: 36 months [% change]a)
|
Main: 21 months
(entire: 36 months)
|
Main: 30 months
(entire: 36 months [% change]a)
|
All prescriptions
Primary care physician panel
Neurologist/psychiatrist panel
|
13,663
(23,844)
740
(1,414)
|
20,742
(25,014 [+4,9])
519
(786 [–44,4])
|
6,193
(10,624)
393
(767)
|
8,305
(10,092 [–5])
243
(372 [–51,5])
|
Incident prescriptions
Primary care physician panel
Neurologist/psychiatrist panel
|
449
(758)
127
(247)
|
554
(652 [–14])
146
(177 [–28,3])
|
206
(353)
77
(152)
|
237
(286 [–19])
79
(99 [–34,9])
|
First-ever prescriptions
Primary care physician panel
Neurologist/psychiatrist panel
|
363
(577)
116
(220)
|
337
(402 [–30,3])
125
(153 [–30,5])
|
157
(252)
71
(133)
|
133
(165 [–34,5])
66
(85 [–36,1])
|
a Change of prescription number in the entire post-implementation period compared with the entire pre-implementation period.
|