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Cerebral aneurysm related to pediatric AIDS. Case report

A.R. Fernandes, A. Favoreto, A. Cruz, M. Aloe, C. Penna [REV NEUROL 2005;41:722-724] PMID: 16355356 DOI: https://doi.org/10.33588/rn.4112.2005304

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Volumen 41 | Number 12 | Nº of views of the article 6.883 | Nº of PDF downloads 431 | Article publication date 16/12/2005

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ABSTRACT

INTRODUCTION Aneurysms, described in pediatric AIDS, are related with bad prognosis with high mortality in 5 months. The twenty reports found in literature were considered late (mean age 9,97 years old) and associated with severe immunological involvement. The mean CD-4 count was 79.17 cells and mean viral load 222,662 copies/mL. Some authors consider this complication associated to the human immunodeficiency virus (HIV), to an opportunistic agent (citomegalovirus and Mycobacterium avium) or due to inflammatory mechanisms related with the immunological improvement.

CASE REPORT This paper present a 9 years old girl with severe AIDS (C-3) and with transient amaurosis related to transient ischemic attacks on ophthalmic artery during her immunological improvement on viral load and CD-4 counts. Necropsy showed aneurysm due to atypical micobateriosis. CONCLUSION. This report highlights the occurrence of this rare but severe HIV complication witch was associated with an opportunistic etiology during an immunological recovery, when inflammatory mediators could play a role. KeywordsAneurysm Cerebrovascular disease Childhood Mycobacterium CategoriesInfecciones Patología vascular

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Nota Clínica

Cerebral aneurysm related to pediatric AIDS. Case report