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How can determination of the carotid intima-media thickness contribute to the process of diagnosing transient ischaemic attacks?

F. Purroy, A. Quílez-Martínez, M. Pardina, I. Suárez-Luis, J. Sanahuja, L. Brieva, G. Piñol-Ripoll [REV NEUROL 2010;51:721-728] PMID: 21157734 DOI: https://doi.org/10.33588/rn.5112.2009572

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Volumen 51 | Number 12 | Nº of views of the article 4.639 | Nº of PDF downloads 542 | Article publication date 16/12/2010

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ABSTRACT

PATIENTS AND METHODS The carotid intima media thickness (IMT) is a new prognostic marker of vascular events. We studied its usefulness in the diagnosis workup of 211 consecutive transient ischemic attack (TIA) patients from the REGITELL registration. GIM was measured according to Mannheim criteria. It was established its relationship to the main prognostic variables described in TIA: ABCD2 scale, symptomatology and etiologic subtypes according to TOAST classification.

RESULTS Men value of carotid IMT was 0.91 ± 0.20 mm. After Bonferroni adjustment, IMT was associated with age of 60 years or older (0.95 ± 0.19 mm; p < 0.001), male sex (0.95 ± 0.20 mm; p = 0.003), ABCD2 scale (p < 0.001), association of risk factors are greater than or equal to 2 (0.94 ± 0.20 mm; p < 0.001), carotid plaque presence (0.98 ± 0.19 mm; p < 0.001), intracranial stenosis (1.09 ± 0.18 mm; p = 0.001), presence of ischemic chronic lesions on head CT (p <0.001) and etiology (p < 0.001). The patients presented with isolated sensory symptoms had significantly lower IMT (0.77 ± 0.18 mm; p = 0.002). Belonging to the third tertile of IMT was only an independent predictor of large-artery atherosclerosis (OR = 3,06; CI 95% = 1.31-7.13; p = 0.01). CONCLUSION. Based on our results, IMT determination seems to not improve the diagnostic accuracy of other ultrasonographic characteristics like the presence of plaques or the degree of stenosis. KeywordsCarotid intima media thickness Diagnosis Transient ischemic attack CategoriesPatología vascular

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Original

How can determination of the carotid intima-media thickness contribute to the process of diagnosing transient ischaemic attacks?